If you are having problems selecting colums to edit/remove from a view in CRM, then the Internet Explorer Enhanced Security Configuration may be the culprit. In IE 6 it is called Internet Security Configuration. A fix that I found worked and you may want to consider, is to go to Add/Remove Programs on the CRM server, select Add/Remove Windows Components and uninstall the Enhanced Security Configuration. After it has been uninstalled, perform an IIS reset (sometimes you need to reboot the server) and you should be good to go, however removing this could have other security related consequences and should be reviewed thoroughly.
